BRIEF INTRODUCTION TO HUMAN IMMUNE SYSTEM

 

Bone Marrow, Pluripotent Hematopoietic Stem Cell

                Innate Immune Response                                     Adaptive Immune Response

               

                Immediate                                                              Delayed 3-7 days

 

                Mediated by Macrophages                                  Mediated by Lymphocytes

                and mast cells                                                        B-Cells, T-Cells

 

                Identical in all Individuals                                   Depends on Exposure to Pathogens

 

                Fixed by Evolution                                                Evolving within individuals

 

                Parasites, worms, chemicals, toxins                    generic viruses, bacteria

                lipoproteins, lipocarbohydrates

                bacterial DNA

 

                Phagocytosis  (engulfment)                                  Activation of Antibodies, CD8 Cells